Document Detail


Management of gout: a 57-year-old man with a history of podagra, hyperuricemia, and mild renal insufficiency.
MedLine Citation:
PMID:  23188030     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Gout is an ancient disease. Despite significant advances in the understanding of its risk factors, etiology, pathogenesis, prevention, and treatment, millions of people with gout experience repeated attacks of acute arthritis and other complications. The incidence of gout is increasing, most likely reflecting increasing rates of obesity and other lifestyle factors, including diet. Comorbid conditions that often accompany gout, including chronic kidney disease and diabetes mellitus, present challenges for the management of gout. Using the case of Mr R, a 57-year-old man with a history of podagra, hyperuricemia, and mild renal insufficiency, the diagnosis and treatment of gout are discussed. For those with moderate to severe gout, urate-lowering treatment can eliminate acute attacks of arthritis and prevent complications. In the near future, it is likely that new risk factors for gout will be identified and new ways of preventing and managing this common disease will become available.
Authors:
Robert H Shmerling
Publication Detail:
Type:  Clinical Conference; Journal Article    
Journal Detail:
Title:  JAMA : the journal of the American Medical Association     Volume:  308     ISSN:  1538-3598     ISO Abbreviation:  JAMA     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2133-41     Citation Subset:  AIM; IM    
Affiliation:
Division of Rheumatology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA. rshmerli@bidmc.harvard.edu
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