| Management of gastropathy and gastric vascular ectasia in portal hypertension. | |
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MedLine Citation:
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PMID: 20682235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Portal hypertensive gastropathy and gastric antral vascular ectasia may cause gastrointestinal hemorrhage in patients with portal hypertension. Whereas the former presents exclusively in patients with portal hypertension, gastric antral vascular ectasia can also be observed in patients with other conditions. Diagnosis is established with upper gastrointestinal endoscopy, although some cases may require a biopsy to confirm the diagnosis. The most frequent manifestation is ferropenic anemia, which may become transfusion dependent. Treatment in portal hypertensive gastropathy is focused on portal pressure reducing drugs, mainly nonselective beta-blockers, whereas in gastric antral vascular ectasia treatment is based on endoscopic ablation. More invasive options can be used if first-line therapies fail, although these should be evaluated on a case-by-case basis. |
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Authors:
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Cristina Ripoll; Guadalupe Garcia-Tsao |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinics in liver disease Volume: 14 ISSN: 1557-8224 ISO Abbreviation: Clin Liver Dis Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-08-04 Completed Date: 2010-12-20 Revised Date: 2012-10-09 |
Medline Journal Info:
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Nlm Unique ID: 9710002 Medline TA: Clin Liver Dis Country: United States |
Other Details:
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Languages: eng Pagination: 281-95 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Digestive Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ablation Techniques
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adverse effects,
methods Adrenergic beta-Antagonists / therapeutic use Anemia, Iron-Deficiency / blood, etiology, physiopathology, therapy Biopsy / adverse effects, methods Blood Transfusion Endoscopes, Gastrointestinal* Gastric Antral Vascular Ectasia* / diagnosis, etiology, physiopathology, therapy Gastrointestinal Hemorrhage* / diagnosis, etiology, physiopathology, therapy Humans Hypertension, Portal / diagnosis*, etiology, physiopathology, therapy* Liver Cirrhosis / complications, physiopathology Stomach Diseases* / diagnosis, etiology, physiopathology, therapy Treatment Outcome |
| Grant Support | |
ID/Acronym/Agency:
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K24 DK002727-01/DK/NIDDK NIH HHS; P30 DK034989/DK/NIDDK NIH HHS; P30 DK034989-219005/DK/NIDDK NIH HHS; P30 DK34989/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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