Document Detail


Management of familial hypertriglyceridemia during pregnancy with plasma exchange.
MedLine Citation:
PMID:  19160449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypertriglyceridemia-induced pancreatitis is a serious complication of familial dyslipidemias. Hormonal influences during pregnancy can compromise otherwise controlled lipid levels in women with familial hypertriglyceridemia and predispose to pancreatitis leading to increased morbidity in both mother and fetus. We report the successful use of therapeutic plasma exchange (TPE) in the management of hypertriglyceridemia during pregnancy resulting in avoidance of pancreatitis and delivery of a healthy term infant. Thirteen TPEs were performed from 19 to 36 weeks gestation to maintain tight control of triglyceride levels.
Authors:
Praveen Sivakumaran; Steven W Tabak; Kimberly Gregory; Samuel H Pepkowitz; Ellen B Klapper
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical apheresis     Volume:  24     ISSN:  1098-1101     ISO Abbreviation:  J Clin Apher     Publication Date:  2009  
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216305     Medline TA:  J Clin Apher     Country:  United States    
Other Details:
Languages:  eng     Pagination:  42-6     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
Affiliation:
Division of Transfusion Medicine, Pathology and Lab Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA. Praveen.Sivakumaran@cshs.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Disease Management
Female
Humans
Hypertriglyceridemia / drug therapy*
Lipid Metabolism, Inborn Errors / drug therapy*
Pancreatitis / prevention & control
Plasma Exchange*
Pregnancy
Pregnancy Complications / diagnosis,  drug therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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