Document Detail

Management of endometrial hyperplasia.
MedLine Citation:
PMID:  20938428     Owner:  NLM     Status:  In-Process    
Endometrial hyperplasia is a commonly seen clinical entity. A great majority of patients present with abnormal uterine bleeding. Unopposed estrogen either from an endogenous or exogenous source is the most important etiologic factor. Etiologic evaluation and cause specific treatment is a must for these patients instead of direct biopsies and treatments. Clinical importance of this pathological entity is the underlying risk of carrying a concomitant genital cancer and the potential risk of progression to endometrial carcinoma during the follow-up. Despite to a great effort on research and a long history of the disease in the medical literature; we still do not have a practical and accurate system available to use during daily practice in order to differentiate the real precancerous lesions. Treatment of endometrial hyperplasia depends on the patient's age, fertility desire and the type of present hyperplasia. Progestagens are still the most commonly used medical treatment modality in these patients. Response rates are higher in cases without atypia. In selected cases, hysterectomy may be performed as a definitive treatment modality. In this review article current management of the endometrial hyperplasia is summarized in the light of associated literature.
M Gültekin; N U Dogan; G Aksan; N Ozgul
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva ginecologica     Volume:  62     ISSN:  0026-4784     ISO Abbreviation:  Minerva Ginecol     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400731     Medline TA:  Minerva Ginecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  433-45     Citation Subset:  IM    
Department of Cancer Control, Turkish Ministry of Health, Ankara, Turkey.
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