| Management of early viable cervical pregnancy. | |
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MedLine Citation:
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PMID: 15777436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate conservative management of early viable cervical pregnancy. DESIGN: Prospective study. SETTING: A tertiary teaching hospital. POPULATION: All cases of cervical pregnancies with fetal cardiac activity presenting to our hospital over six years. METHODS: All cases were managed with trans-abdominal intra-amniotic injection of 25 mg of methotrexate under ultrasound guidance. Follow up sonographic examinations and serum beta-hCG measurements were performed every three days. Cervical curettage was performed after two follow up ultrasound examinations had shown a dead fetus and a regressing gestational sac as well as declining beta-hCG levels. Patients were managed as outpatients. MAIN OUTCOME MEASURES: Successful management and need for hospitalisation. RESULTS: Nine cases were encountered. Two required a second injection of methotrexate for persistent fetal cardiac activity and serum beta-hCG rise in the follow up examination. We did not observe any side effects and no patient required admission to the hospital. CONCLUSIONS: Intra-amniotic methotrexate injection and subsequent cervical curettage after one week is a successful alternative for the management of cervical pregnancies. |
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Authors:
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Spiros Mesogitis; Athanasios Pilalis; George Daskalakis; Nikolaos Papantoniou; Aris Antsaklis |
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Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 112 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-03-21 Completed Date: 2005-05-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 409-11 Citation Subset: AIM; IM |
Affiliation:
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1st Department of Obstetrics and Gynecology, University of Athens, Alexandra Hospital, Greece. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents, Nonsteroidal
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administration & dosage* Abortion, Therapeutic / methods* Adult Amnion Curettage / methods* Female Humans Injections Methotrexate / administration & dosage* Postpartum Hemorrhage / prevention & control Pregnancy Pregnancy, Ectopic / therapy* Prospective Studies Ultrasonography, Interventional / methods Ultrasonography, Prenatal / methods |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents, Nonsteroidal; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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