Document Detail

Management of early ectopic pregnancy.
MedLine Citation:
PMID:  7513658     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Management of early ectopic pregnancy was investigated in a multicenter, prospective study. METHODS: Serum beta-hCG levels were monitored after therapy and correlated to the type of management, gestational age, and initial serum beta-hCG levels in 119 patients with ectopic pregnancies detected at 5-7 postmenstrual weeks. RESULTS: Salpingectomy was performed in 16 patients. No post-operative complications were reported. After conservative laparoscopic surgery of 51 ectopic pregnancies, 9 (18%) had delayed decrease or an increase of serum beta-hCG levels. Re-operations were performed in 4 (7%) patients. Similar findings were noted in 2/6 patients after conservative operations performed by laparotomy. Intrachorionic injection treatment was successful in 17/18 ectopic pregnancies, and expectant management in 7/8 patients with initial serum beta-hCG levels below 250 mIU/ml. CONCLUSIONS: Persistence of trophoblastic activity is a potential complication of conservative surgical treatment of ectopic pregnancy. A detailed diagnosis as early as 6-7 post-menstrual weeks may be the key for future non-surgical management of ectopic pregnancy.
L W Popp; A Colditz; R Gaetje
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  44     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-06-09     Completed Date:  1994-06-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
Clinic Dr. Guth, Juergensallee, Hamburg, Germany.
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MeSH Terms
Abortifacient Agents / administration & dosage
Abortion, Therapeutic / methods
Chorionic Gonadotropin / blood
Chorionic Gonadotropin, beta Subunit, Human
Chorionic Villi
Fallopian Tubes / surgery
Peptide Fragments / blood
Pregnancy Trimester, First
Pregnancy, Tubal / epidemiology,  surgery,  therapy*
Prospective Studies
Tumor Markers, Biological / blood
Reg. No./Substance:
0/Abortifacient Agents; 0/Chorionic Gonadotropin; 0/Chorionic Gonadotropin, beta Subunit, Human; 0/Peptide Fragments; 0/Tumor Markers, Biological; 3397-23-7/Ornipressin; 59-05-2/Methotrexate

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