Document Detail


Management of dyslipidemia in patients with complicated metabolic syndrome.
MedLine Citation:
PMID:  16098839     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
As the prevalence of the metabolic syndrome increases, 2 comorbid conditions--hepatic steatosis and human immunodeficiency virus (HIV) lipodystrophy--have become difficult clinical challenges. Dyslipidemia in patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis may improve with use of statins, fibrates, niacin, and thiazolidinediones, but the data are presently very limited. HIV lipodystrophy is associated with a marked risk of coronary artery disease (CAD), and more aggressive management of the dyslipidemia is likely necessary to improve the prognosis.
Authors:
Michael H Davidson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of cardiology     Volume:  96     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-15     Completed Date:  2005-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  22E-25E     Citation Subset:  AIM; IM    
Affiliation:
Division of Preventive Cardiology, Department of Medicine, Rush University Medical Center, Chicago, Illinois 60612, USA. michaeldavidson@radiantresearch.com
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MeSH Terms
Descriptor/Qualifier:
Clofibric Acid / therapeutic use*
Fatty Liver / complications
HIV-Associated Lipodystrophy Syndrome / complications
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Hyperlipidemias / drug therapy*
Metabolic Syndrome X / complications*
Niacin / therapeutic use*
Thiazolidinediones / therapeutic use*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Thiazolidinediones; 59-67-6/Niacin; 882-09-7/Clofibric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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