Document Detail


Management of cutaneous side effects of EGFR inhibitors: recommendations from a German expert panel for the primary treating physician.
MedLine Citation:
PMID:  21059173     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Inhibitors of the epidermal growth factor receptor (EGFR) are increasingly used in the treatment of various entities of malignant tumors. Patients treated with EGFR inhibitors very likely develop cutaneous side effects. The development of a papulopustular, follicular exanthema during the first weeks of therapy correlates with therapeutic benefit. However, this exanthema and other cutaneous side effects can impair the quality of life of the patient and might limit the therapy with the EGFR inhibitor. For an optimal therapeutic benefit and quality of life an adequate management of cutaneous side effects is necessary. A panel of German dermatologists developed on the basis of personal experience and current literature consensus recommendations for the management of cutaneous side effects of EGFR inhibitors.
Authors:
Ralf Gutzmer; Jürgen C Becker; Alexander Enk; Claus Garbe; Axel Hauschild; Martin Leverkus; Georg Reimer; Regina Treudler; Athanasios Tsianakas; Claas Ulrich; Andreas Wollenberg; Bernhard Homey
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Publication Detail:
Type:  Journal Article     Date:  2010-11-08
Journal Detail:
Title:  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG     Volume:  9     ISSN:  1610-0387     ISO Abbreviation:  J Dtsch Dermatol Ges     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101164708     Medline TA:  J Dtsch Dermatol Ges     Country:  Germany    
Other Details:
Languages:  eng; ger     Pagination:  195-203     Citation Subset:  IM    
Copyright Information:
© The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.
Affiliation:
Department of Dermatology, Allergy and Venereology, Skin Cancer Center, Hannover Medical School, Germany. gutzmer.ralf@mh-hannover.de
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