Document Detail

Management of coronary artery disease in patients with chronic kidney disease.
MedLine Citation:
PMID:  19886333     Owner:  NLM     Status:  MEDLINE    
Patients with chronic kidney disease (CKD) are considered to belong to the highest risk group for the development of cardiovascular events. These patients should be subject to aggressive risk-factor modification. However, management of coronary artery disease in patients with CKD can be uniquely challenging. Many of the medications used in the treatment and prevention of coronary artery disease are metabolized or excreted by the kidney. Thus, patients with CKD are more likely to experience adverse effects from any attempt to aggressively modify risk factors for coronary artery disease. Little is known regarding revascularization in patients with CKD. Patients with CKD may benefit from off-pump strategies during coronary artery bypass. Percutaneous coronary intervention in patients with CKD is associated with lower procedural success and increased peri-procedural myocardial infarction, ischemia, and target vessel revascularization. In this review, we discuss the unique challenges of managing coronary artery disease in patients with CKD.
Walter C Coats; Sara Z Baig; Martin A Alpert; Kul Aggarwal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances in peritoneal dialysis. Conference on Peritoneal Dialysis     Volume:  25     ISSN:  1197-8554     ISO Abbreviation:  Adv Perit Dial     Publication Date:  2009  
Date Detail:
Created Date:  2009-11-05     Completed Date:  2009-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104803     Medline TA:  Adv Perit Dial     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  125-8     Citation Subset:  IM    
Department of Internal Medicine, Division of Cardiovascular Medicine, University of Missouri-Columbia, 65212, USA.
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MeSH Terms
Acute Coronary Syndrome / complications,  therapy
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Artery Disease / blood,  complications,  therapy*
Dyslipidemias / complications,  drug therapy
Kidney Failure, Chronic / complications*
Renal Insufficiency, Chronic / complications

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