| Management of cold haemolytic syndrome. | |
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MedLine Citation:
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PMID: 17561970 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most haemolytic disease is mediated by immunoglobulin G (IgG) antibodies and leads to red blood cell destruction outside of the circulatory system. However, rare syndromes, such as paroxysmal cold haemoglobinuria, show IgG antibodies causing intravascular destruction. Haemolysis may also occur because of immunoglobulin M antibodies. Historically, these antibodies have been termed 'cold agglutinins' because they cause agglutination of red blood cells at 3 degrees C. Cold agglutinin haemolytic anaemia has been associated with a number of autoimmune and lymphoproliferative disorders, and its management differs substantially from warm antibody-mediated haemolytic anaemia. This review of cold haemolytic syndromes describes new therapies and clinical strategies to determine a correct diagnosis. |
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Authors:
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Morie A Gertz |
Publication Detail:
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Type: Journal Article; Review Date: 2007-06-11 |
Journal Detail:
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Title: British journal of haematology Volume: 138 ISSN: 0007-1048 ISO Abbreviation: Br. J. Haematol. Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-30 Completed Date: 2007-09-28 Revised Date: 2008-12-16 |
Medline Journal Info:
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Nlm Unique ID: 0372544 Medline TA: Br J Haematol Country: England |
Other Details:
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Languages: eng Pagination: 422-9 Citation Subset: IM |
Affiliation:
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Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA. gertz.morie@mayo.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic, Autoimmune
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drug therapy,
immunology,
therapy* Autoantibodies / immunology Cryoglobulins / immunology Glucocorticoids / therapeutic use Hemolysis Humans |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Cryoglobulins; 0/Glucocorticoids; 0/cold agglutinins |
| Comments/Corrections | |
Comment In:
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Br J Haematol. 2008 Aug;142(4):668
[PMID:
18573114
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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