Document Detail

Management of chronic atherosclerotic mesenteric ischemia.
MedLine Citation:
PMID:  21500174     Owner:  NLM     Status:  MEDLINE    
Chronic mesenteric ischemia (CMI) is most likely caused by atherosclerosis and less frequently by external compression, fibromuscular dysplasia and vasculitis. Symptomatic CMI is an uncommon, potentially under-diagnosed condition caused by fixed stenoses or occlusion of in most conditions at least two visceral arteries. If only one of the three major bowel providing arteries - the celiac trunk, the superior and inferior mesenteric arteries - is affected, the patient is usually asymptomatic due to a tight collateral network. Symptoms and clinical signs of CMI may vary from the classical triad of postprandial pain, weight loss and upper abdominal bruit to nonspecific symptoms thus frequently resulting in delayed diagnosis. Established non-invasive diagnostic means are duplex ultrasound or CT- and MR-angiography offering excellent three dimensional reconstruction of the vessel pathology facilitating the decision for the appropriate revascularisation strategy. During the last decade, despite higher restenosis rates endovascular revascularization has replaced surgical revascularization as therapy of choice in most centers. If untreated CMI of atherosclerotic origin is associated with a high morbidity and mortality. This manuscript reviews the most relevant clinical aspects of the disease and the current practice of diagnosis and treatment of CMI.
T Zeller; R Macharzina
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  VASA. Zeitschrift für Gefässkrankheiten     Volume:  40     ISSN:  0301-1526     ISO Abbreviation:  VASA     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-04-18     Completed Date:  2011-06-07     Revised Date:  2012-10-19    
Medline Journal Info:
Nlm Unique ID:  0317051     Medline TA:  Vasa     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  99-107     Citation Subset:  IM    
Department Angiology, Herz-Zentrum Bad Krozingen, Bad Krozingen, Germany.
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MeSH Terms
Atherosclerosis / complications*
Endovascular Procedures*
Ischemia / diagnosis,  etiology,  therapy
Treatment Outcome
Vascular Diseases / diagnosis,  etiology,  therapy
Vascular Surgical Procedures*

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