| Management of cervical adenocarcinoma in situ during pregnancy. | |
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MedLine Citation:
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PMID: 15902134 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Adenocarcinoma in situ (AIS) is a precursor of invasive disease that is being more frequently diagnosed during the reproductive years. Few reports have described the treatment of this condition in gravid women. The purpose of this study was to review our collective experience managing cervical AIS during pregnancy. STUDY DESIGN: Retrospective medical record review of all women diagnosed with AIS during pregnancy from 1995 to 2004 at 3 academic institutions. RESULTS: Eleven women with a median age of 32 years were identified. Five who received a diagnosis in the early second trimester underwent uncomplicated cold knife conization (CKC) at 14 to 19 weeks' gestation. Six patients underwent postpartum CKC. All 11 women delivered at term. One patient undergoing postpartum CKC required radical hysterectomy for stage IB1 cervical adenocarcinoma. Four subsequent pregnancies occurred among patients having fertility-sparing surgery. CONCLUSION: Management of cervical AIS during pregnancy by early second trimester CKC is safe for mother and fetus. |
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Authors:
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Robin A Lacour; Elizabeth I O Garner; Kelly L Molpus; Raheela Ashfaq; John O Schorge |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 192 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-05-19 Completed Date: 2005-06-24 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1449-51 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75390-9032, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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pathology,
surgery* Adult Conization* Delivery, Obstetric Female Fertility Humans Hysterectomy Neoplasm Staging Postoperative Period Postpartum Period Pregnancy Pregnancy Complications, Neoplastic / surgery* Pregnancy Trimester, Second Retrospective Studies Uterine Cervical Neoplasms / pathology, surgery* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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