Document Detail


Management of cardiogenic shock: focus on tissue perfusion.
MedLine Citation:
PMID:  19591748     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiogenic shock (CS) may result from ischemic heart disease, cardiomyopathy, valvular heart disease, inflammation, myocardial contusion, and cardiac surgery. CS is the leading cause of in-hospital death in patients with acute myocardial infarction. Although early revascularization strategies have resulted in a better prognosis, in-hospital mortality from CS remains exceptionally high. Notably, long-term annual mortality is similar in survivors of CS relative to patients with myocardial infarction without shock. This underlines the importance of aggressive support of the failing heart in the acute phase of CS. Because CS reflects a state of hypoperfusion induced by heart failure, management of CS should aim at improving cardiac function as well as at optimization of tissue perfusion. This review evaluates the current treatment of CS. In addition, novel approaches to monitor and modulate peripheral circulation at the bedside are highlighted. It is expected that these techniques will improve our understanding of the pathogenesis of CS and will offer new opportunities to guide therapy in CS patients to improve long-term prognosis.
Authors:
Corstiaan A den Uil; Wim K Lagrand; Suzanne D A Valk; Peter E Spronk; Maarten L Simoons
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current problems in cardiology     Volume:  34     ISSN:  1535-6280     ISO Abbreviation:  Curr Probl Cardiol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-13     Completed Date:  2009-09-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701802     Medline TA:  Curr Probl Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  330-49     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cardiotonic Agents / therapeutic use
Coronary Circulation*
Humans
Myocardial Reperfusion*
Perfusion
Risk Factors
Shock, Cardiogenic / drug therapy,  etiology,  therapy*
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; 0/Vasodilator Agents
Comments/Corrections
Comment In:
Curr Probl Cardiol. 2009 Aug;34(8):327   [PMID:  19591747 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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