Document Detail

Management of brain abscess in children: review of 130 cases over a period of 21 years.
MedLine Citation:
PMID:  1458499     Owner:  NLM     Status:  MEDLINE    
The data on 130 children with brain abscesses treated over 21 years (1970-1990) were analyzed retrospectively. The whole group included four infants. Chronic ear infection and cyanotic congenital heart disease were the most common predisposing factors. In infants, meningitis and/or ventriculitis were dominant in the etiopathogenesis. Cases were evaluated according to the treatment received and also according to time periods. More than half of the patients (n = 74) in this series were treated by primary or secondary excision. Computed tomography (CT) facilitated the diagnosis and helped the planning of treatment. Aspiration gained increasing credit after the advent of CT. Microorganisms could be identified in 54% of the cultured specimens. Staphylococci, streptococci and Proteus were the dominating microorganisms. Penicillin and chloramphenicol have long been the mainstay of antimicrobial therapy but have recently been replaced by third-generation cephalosporins and sulbactam-ampicillin combinations. Overall mortality was 15.5% but showed a decline from 30% in the pre-CT era to 6% in the last 5 years and to zero in the last three. Neither the location nor associated heart disease contributed to the mortality, but mortality among infants was as high as 50%.
I H Tekkök; A Erbengi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  8     ISSN:  0256-7040     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-01-13     Completed Date:  1993-01-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  411-6     Citation Subset:  IM    
Department of Neurosurgery, Hacettepe University School of Medicine, Ankara, Turkey.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Anti-Bacterial Agents / therapeutic use
Brain Abscess / etiology,  microbiology,  surgery*
Child, Preschool
Follow-Up Studies
Retrospective Studies
Survival Analysis
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents

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