| Management of brain abscess in children: review of 130 cases over a period of 21 years. | |
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MedLine Citation:
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PMID: 1458499 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The data on 130 children with brain abscesses treated over 21 years (1970-1990) were analyzed retrospectively. The whole group included four infants. Chronic ear infection and cyanotic congenital heart disease were the most common predisposing factors. In infants, meningitis and/or ventriculitis were dominant in the etiopathogenesis. Cases were evaluated according to the treatment received and also according to time periods. More than half of the patients (n = 74) in this series were treated by primary or secondary excision. Computed tomography (CT) facilitated the diagnosis and helped the planning of treatment. Aspiration gained increasing credit after the advent of CT. Microorganisms could be identified in 54% of the cultured specimens. Staphylococci, streptococci and Proteus were the dominating microorganisms. Penicillin and chloramphenicol have long been the mainstay of antimicrobial therapy but have recently been replaced by third-generation cephalosporins and sulbactam-ampicillin combinations. Overall mortality was 15.5% but showed a decline from 30% in the pre-CT era to 6% in the last 5 years and to zero in the last three. Neither the location nor associated heart disease contributed to the mortality, but mortality among infants was as high as 50%. |
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Authors:
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I H Tekkök; A Erbengi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery Volume: 8 ISSN: 0256-7040 ISO Abbreviation: Childs Nerv Syst Publication Date: 1992 Oct |
Date Detail:
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Created Date: 1993-01-13 Completed Date: 1993-01-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8503227 Medline TA: Childs Nerv Syst Country: GERMANY |
Other Details:
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Languages: eng Pagination: 411-6 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Hacettepe University School of Medicine, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenal Cortex Hormones / therapeutic use Anti-Bacterial Agents / therapeutic use Brain Abscess / etiology, microbiology, surgery* Child Child, Preschool Female Follow-Up Studies Humans Incidence Infant Male Retrospective Studies Survival Analysis |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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