Document Detail


Management of atherosclerotic renal artery stenosis.
MedLine Citation:
PMID:  20828354     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The management of atherosclerotic renal artery stenosis is controversial. Although it may appear intuitive that restoring normal blood flow to the kidney(s) is the treatment of choice, there are no data showing an obvious advantage of interventional therapy compared with medical therapy. In this article, we discuss the most recent advances in the treatment of atherosclerotic renal artery stenosis with a focus on randomized studies comparing medical treatment with angioplasty/stenting, particularly in patients with underlying renal dysfunction. The available data are still of limited quality but provide support against indiscriminate use of interventions, as these treatments appear no better than best medical treatment that focuses on blood pressure control, use of blockers of the renin-angiotensin system, and aggressive cardiovascular risk management.
Authors:
Aldo J Peixoto; Laura M Ditchel; Sergio F F Santos
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Expert review of cardiovascular therapy     Volume:  8     ISSN:  1744-8344     ISO Abbreviation:  Expert Rev Cardiovasc Ther     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-10     Completed Date:  2010-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101182328     Medline TA:  Expert Rev Cardiovasc Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  1317-24     Citation Subset:  IM    
Affiliation:
Medical Service, VA Connecticut Healthcare System, West Haven, CT, USA. aldo.peixoto@yale.edu
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MeSH Terms
Descriptor/Qualifier:
Angioplasty, Balloon
Angiotensin Receptor Antagonists / therapeutic use
Atherosclerosis / complications,  drug therapy*
Cardiovascular Agents / therapeutic use*
Humans
Renal Artery Obstruction / etiology,  therapy*
Renal Insufficiency / complications
Stents
Chemical
Reg. No./Substance:
0/Angiotensin Receptor Antagonists; 0/Cardiovascular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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