Document Detail

Management of asthma during pregnancy.
MedLine Citation:
PMID:  23129568     Owner:  NLM     Status:  Publisher    
Asthma is an inflammatory lung condition that is the most common chronic disease affecting pregnancy. The changes in pulmonary physiology during pregnancy include increased minute ventilation, decreased functional residual capacity, increased mucus production, and airway mucosa hyperemia and edema. Pregnancy is also associated with a physiological suppression of the immune system. Many studies have described the heterogeneous immune system response in women with asthma during pregnancy, which partly explains why asthma has been shown to worsen, improve, or remain stable in equal proportions of women during pregnancy. Asthma may be associated with poor maternal and fetal outcomes. However, better maternal and fetal outcomes are observed with better asthma control. Asthma controller medications are generally thought to be safe during pregnancy, but limited data are available for some of the medicines. Newer medications like omalizumab open avenues for the treatment of asthma, but also pose a challenge, as there is limited experience with their use. Therefore, a multidisciplinary approach, including obstetricians, asthma specialists, and pediatricians should collaborate with the patient to carefully weigh the risks and benefits to determine an optimal management plan for each individual patient. The aim of this review article is to summarize the most recent literature about the immunological changes that occur during pregnancy, physiological and clinical implications of asthma on pregnancy, and asthma management and medication use in pregnant women.
Diego J Maselli; Sandra G Adams; Jay I Peters; Stephanie M Levine
Related Documents :
532438 - Soluble fibrin-monomer complexes in normal pregnancy.
20586548 - Haemostatic and cytokine changes in gestational diabetes mellitus.
9175178 - Essential fatty acid status in plasma phospholipids of mother and neonate after multipl...
6749878 - Somatomedins in pregnancy: a cross-sectional study of insulin-like growth factors i and...
21787448 - Impact of maternal supplementation with probiotics during pregnancy on atopic eczema in...
22565238 - The pregnant patient with congenital heart disease.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-5
Journal Detail:
Title:  Therapeutic advances in respiratory disease     Volume:  -     ISSN:  1753-4666     ISO Abbreviation:  Ther Adv Respir Dis     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316317     Medline TA:  Ther Adv Respir Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Division of Pulmonary Diseases and Critical Care, University of Texas Health Science Center at San Antonio, Merton Minter, TX, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Recent advances in the development of Raman spectroscopy for deep non-invasive medical diagnosis.
Next Document:  Tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hyperte...