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Management of the adverse effects of lenalidomide in multiple myeloma.
MedLine Citation:
PMID:  21431626     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The introduction of new agents in the treatment of multiple myeloma, such as thalidomide, bortezomib, or lenalidomide, has represented an important step forward in the management of this disease, with improvement in both treatment response and patient survival. On the other hand, when new drugs are used it is very important to know their associated toxicity, since adequate management of the adverse effects can help to avoid unnecessary treatment interruptions - thereby undoubtedly contributing to improvement in the efficacy of therapy. The present study reviews the main hematological and nonhematological adverse effects potentially associated with the use of lenalidomide in its most common combinations used for the treatment of multiple myeloma, and the recommendations for dealing with such effects.
Authors:
Ana Pilar González Rodríguez
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Publication Detail:
Type:  Journal Article     Date:  2011-03-09
Journal Detail:
Title:  Advances in therapy     Volume:  28 Suppl 1     ISSN:  1865-8652     ISO Abbreviation:  Adv Ther     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8611864     Medline TA:  Adv Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  T    
Affiliation:
Hematology Department, Hospital Central de Asturias, Oviedo, Asturias, Spain, anapilargonzalez@gmail.com.
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