| Management of acute ulcerative and necrotising herpes simplex and zoster keratitis with amniotic membrane transplantation. | |
| | |
MedLine Citation:
|
PMID: 14507749 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIM: To report promoted healing of acute ulcerative and necrotising herpetic keratitis after amniotic membrane transplantation (AMT). METHODS: Retrospective, non-comparative case series of seven patients with acute ulcerative and necrotising herpetic stromal keratitis. Single or multilayer AMT with epithelial side facing up was performed. The main outcome measures were wound healing of the corneal ulcers and decrease of stromal inflammation. RESULTS: The mean follow up was 10.7 (SEM 1.4) months (range 5-15 months). AMT was performed once in five cases, and twice in further two. Improvement of stromal inflammation was noted within 16.4 (2.5) days (range 7-28 days). Epithelial defects healed within a mean of 17 (2.7) days (range 7-28 days). Vision improved in all but two patients. No serious side effects occurred during the follow up. CONCLUSIONS: Although performed in an uncontrolled and non-randomised series of patients, these findings indicate that the AMT shows promise in selected cases for the restoration of ocular surface integrity, reduction of stromal inflammation, and improvement of vision in acute ulcerative and necrotising herpetic keratitis. |
| | |
Authors:
|
A Heiligenhaus; H Li; E E Hernandez Galindo; J M Koch; K-P Steuhl; D Meller |
Related Documents
:
|
358369 - Clinical results of parietal cell vagotomy and selective vagotomy with pyloroplasty in ... 19141719 - Effectiveness and safety of using podikon digital silicone padding in the primary preve... 3804019 - Cancer surveillance of patients with longstanding ulcerative colitis: a clinical, endos... 19375519 - Mesalamine once daily is more effective than twice daily in patients with quiescent ulc... 8454789 - Compression stockings and non-continuous use of polyurethane foam dressings for the tre... 15299989 - Changes in patient's quality of life comparing conservative and surgical treatment of v... 21030049 - Tonsillectomy does not improve bedwetting: results of a prospective controlled trial. 14765849 - Predictors of outcome in patients with prosthetic valve dysfunction. 19147419 - The orbicularis oculi muscle flap: its use for treatment of lagophthalmos and a review ... |
Publication Detail:
|
Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The British journal of ophthalmology Volume: 87 ISSN: 0007-1161 ISO Abbreviation: Br J Ophthalmol Publication Date: 2003 Oct |
Date Detail:
|
Created Date: 2003-09-25 Completed Date: 2003-11-24 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0421041 Medline TA: Br J Ophthalmol Country: England |
Other Details:
|
Languages: eng Pagination: 1215-9 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, St Franziskus Hospital, Hohenzollernring 74, 48145 Muenster, Germany. arnd.heiligenhaus@t-online.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Aged Biological Dressings* Corneal Ulcer / therapy, virology Female Follow-Up Studies Humans Keratitis, Herpetic / physiopathology, therapy* Male Middle Aged Retrospective Studies Treatment Outcome Vision Disorders / physiopathology, therapy Wound Healing |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Penetrating keratoplasty in children: visual and graft outcome.
Next Document: Automated identification of diabetic retinal exudates in digital colour images.