Document Detail

Mammary gland growth and response to hormones in mastomys compared with mice.
MedLine Citation:
PMID:  2761236     Owner:  NLM     Status:  MEDLINE    
Mammary gland growth with or without hormone manipulation was examined in virgin mastomys (Praomys (mastomys) natalensis) and compared with C3H/He mice having a low mammary tumor incidence. Mammary glands of mastomys consisted mostly of duct systems even at 720 days of age, whereas conspicuous formation of normal end-buds and preneoplastic hyperplastic alveolar nodules were seen in the glands of mice after 180 days of age. Mammary glands of mastomys showed a higher response to estrogen or progesterone rather than prolactin, which is much different from other rodents.
H Nagasawa; U Koshimizu; M Watanabe; K Tokuda; H Sumita; Y Kano
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Laboratory animal science     Volume:  39     ISSN:  0023-6764     ISO Abbreviation:  Lab. Anim. Sci.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-09-14     Completed Date:  1989-09-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1266503     Medline TA:  Lab Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  313-7     Citation Subset:  IM    
Experimental Animal Research Laboratory, Meiji University, Kanagawa, Japan.
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MeSH Terms
Age Factors
Body Weight
Estrogens / blood*
Mammary Glands, Animal / growth & development*
Mice, Inbred C3H / growth & development
Muridae / growth & development*
Organ Size
Progesterone / blood*
Prolactin / blood*
Reg. No./Substance:
0/Estrogens; 57-83-0/Progesterone; 9002-62-4/Prolactin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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