Document Detail


Mammary carcinoma with osteoclast-like giant cells: a study of four cases and a review of literature.
MedLine Citation:
PMID:  16138376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mammary carcinoma with osteoclast-like giant cells (OGCs) is an extremely rare tumor. To the best of our knowledge, only 45 cases have been reported in the literature. Here we report four additional cases of this tumor. The fine-needle aspiration cytology was performed in all four cases, showing an abundance of giant cells and mononucleated stromal cells in intimate association with low- or medium-grade malignant epithelial clusters. Histologically, cribriform patterns predominated in three cases. In one case, OGCs were more pronounced in the vicinity of ductal carcinoma in situ accompanied by marked stromal angiogenesis. This study, as well as review of the literature, underlines the characteristic features of this rare histologic type of carcinoma.
Authors:
Ning Cai; June Koizumi; Madeline Vazquez
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  33     ISSN:  8755-1039     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-07     Completed Date:  2005-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
Copyright Information:
Copyright 2005 Wiley-Liss, Inc
Affiliation:
Department of Pathology, New York Presbyterian Hospital, Weill Cornell Medical Center, New York, New York 10021, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Biopsy, Fine-Needle
Breast Neoplasms / pathology*
Carcinoma, Ductal, Breast / pathology*
Female
Giant Cells / pathology*
Humans
Middle Aged
Osteoclasts / pathology*
Stromal Cells / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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