Document Detail

Mammalian skeletal muscle: long-lasting contractures and potentiated tetani produced by conditioning with weak acid anions.
MedLine Citation:
PMID:  6617807     Owner:  NLM     Status:  MEDLINE    
Reversible contractures can be induced in slow mammalian muscles by manipulations that probably generate a long-lasting alkalinization of the muscle cell interior. Such contractures reach about 1/4 of the tetanic force, P0, and last 10 times longer than potassium contractures. While in contracture, the muscle fibers have high resting potentials so that they can be electrically stimulated. Tetanic force is then increased and added to that of the contracture so that total force may reach 2 P0. This level of potentiation has not been reached by any previously-known method.
H Lorković; R Pfister; R Rüdel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experientia     Volume:  39     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1072-6     Citation Subset:  IM    
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MeSH Terms
Anions / pharmacology*
Caffeine / pharmacology
Electric Stimulation
Hydrogen-Ion Concentration*
Membrane Potentials
Muscle Contraction / drug effects*
Potassium / pharmacology
Reg. No./Substance:
0/Anions; 58-08-2/Caffeine; 7440-09-7/Potassium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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