Document Detail


Malignant vaginal melanoma with metastases to the papilla of vater in a dialysis patient: a case report.
MedLine Citation:
PMID:  21325769     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Malignant vaginal melanoma is an extremely rare clinical condition, with less than 150 cases reported to date. A dialysis patient had primary vaginal melanoma with metastases to the papilla of Vater. Gastroduodenoscopy revealed a polypoid tumor. Histological findings revealed vimentin, S-100 protein, HMB45, MelanA-positive sarcoma-like cells. This staining pattern indicated that this tumor was a malignant melanoma of the papilla. Analysis of an autopsy specimen of the papilla of Vater revealed metastasis from the primary vaginal melanoma. Metastasis of a malignant tumor to the gastrointestinal tract, especially to the papilla, is uncommon. Melanoma should be considered in the differential diagnosis of primary gastrointestinal tract malignancy.
Authors:
Hitoshi Nakayama; Shigeru Miyazaki; Hiroshi Kikuchi; Noriko Saito; Hisaki Shimada; Shinji Sakai; Masashi Suzuki; Kakuhei Kimura
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Publication Detail:
Type:  Journal Article     Date:  2011-02-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  50     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2011  
Date Detail:
Created Date:  2011-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  345-9     Citation Subset:  IM    
Affiliation:
Division of Nephrology and Hypertension, Department of Internal Medicine, Shinrakuen Hospital, Japan.
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