Document Detail

Malignant transformation of high-grade astrocytoma associated with neurocysticercosis in a patient with Turcot syndrome.
MedLine Citation:
PMID:  17138070     Owner:  NLM     Status:  MEDLINE    
A 45-year-old woman with anaplastic astrocytoma was clinically diagnosed with Turcot syndrome, and subsequently developed simultaneous neurocysticercosis and malignant transformation to glioblastoma. The parasitic cysts and glioblastoma were microsurgically removed. Histological examination of surgical specimens revealed neurocysticercosis between the normal brain tissue and glioblastoma. The clinical course and histological findings suggest that the parasitic infection and/or genetic changes contributed to the malignant transformation of the astrocytic tumour.
Kuniyasu Niizuma; Miki Fujimura; Toshihiro Kumabe; Tominaga Tominaga
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  14     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2006-12-01     Completed Date:  2007-03-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  53-5     Citation Subset:  IM    
Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1-1, Seiryo-machi, Aoba-ku, Sendai 980-8574, Japan.
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MeSH Terms
Astrocytoma / complications,  pathology*,  surgery
Brain Neoplasms / complications,  pathology*,  surgery
Cell Transformation, Neoplastic / pathology*
Fatal Outcome
Glioblastoma / complications,  pathology*,  surgery
Magnetic Resonance Imaging
Middle Aged
Neurocysticercosis / parasitology,  pathology*,  surgery
Neurosurgical Procedures

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