Document Detail

Malignant struma ovarii: The west of Scotland experience and review of literature with focus on postoperative management.
MedLine Citation:
PMID:  22883659     Owner:  NLM     Status:  In-Data-Review    
Introduction: Malignant struma ovarii is an extremely rare ovarian tumour containing malignant thyroid carcinoma within differentiated thyroid tissue, as the predominant tissue type. Surgery for suspected ovarian tumour and incidental pathological diagnosis is the most common presentation. Evidence supporting any particular approach to the clinical management of this condition is limited, mainly consisting of case reports, small series or pathological case series. There is no randomised evidence for postoperative management in view of the rarity of this condition. The opinion is divided between conservative management versus total thyroidectomy and radio-iodine ablation. Methods: We carried out a retrospective review of our series with focus on postoperative management of this rare condition. A review of existing literature was also carried out. Results: Six patients with a median age of 52 years presented with various symptoms of abdominal pain, pressure or menstrual problems. After the initial gynaecological resection and specialised pathology review, they were subsequently treated with total thyroidectomy and administration of radioactive iodine. All of these six patients are in remission at a median follow up of 60 months. Conclusion: We favour aggressive postoperative management with total thyroidectomy and radioactive iodine, and long-term follow up of these patients.
Raj K Shrimali; Ghazia Shaikh; Nick S Reed
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Publication Detail:
Type:  Journal Article     Date:  2012-05-28
Journal Detail:
Title:  Journal of medical imaging and radiation oncology     Volume:  56     ISSN:  1754-9485     ISO Abbreviation:  J Med Imaging Radiat Oncol     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101469340     Medline TA:  J Med Imaging Radiat Oncol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  478-82     Citation Subset:  IM    
Copyright Information:
© 2012 The Authors. Journal of Medical Imaging and Radiation Oncology © 2012 The Royal Australian and New Zealand College of Radiologists.
Department of Clinical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UK.
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