Document Detail

Malignant spinal neurofibrosarcoma.
MedLine Citation:
PMID:  10752112     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: A report of a case of metastatic spinal neurofibrosarcoma. OBJECTIVE: To document metastatic neurofibrosarcoma as a cause of spinal cord compression and to review the literature. SUMMARY OF BACKGROUND DATA: Three previously reported cases of metastatic neurofibrosarcoma of the spine were reviewed. METHODS: The patient's clinical record and radiologic investigations as well as the result of a search of the English literature are reported. Magnetic resonance images, computed tomographic scans, and histology photomicrographs are displayed. RESULTS: Paraparesis developed in this patient, due to a posterior extradural thoracic spinal cord compression by a neurofibrosarcoma believed to be metastatic from a neurofibrosarcoma of the femoral nerve. CONCLUSIONS: Malignant spinal metastasis remains a rare complication of neurofibromatosis, with a very poor prognosis.
R Kett-White; J L Martin; E W Jones; C O'Brien
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Spine     Volume:  25     ISSN:  0362-2436     ISO Abbreviation:  Spine     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-06-06     Completed Date:  2000-06-06     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  752-5     Citation Subset:  IM    
Department of Neurosurgery, Morriston Hospital, Swansea, Wales, United Kingdom.
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MeSH Terms
Fatal Outcome
Magnetic Resonance Imaging
Middle Aged
Neurofibroma / pathology
Neurofibrosarcoma / complications,  diagnosis,  secondary*,  surgery
Soft Tissue Neoplasms / pathology
Spinal Cord Compression / etiology,  surgery
Spinal Cord Neoplasms / complications,  diagnosis,  secondary*,  surgery
Tomography, X-Ray Computed

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