Document Detail

Malignant peritoneal mesothelioma. A clinical and laparoscopic study of ten cases.
MedLine Citation:
PMID:  2966056     Owner:  NLM     Status:  MEDLINE    
A retrospective study of 10 cases of malignant peritoneal mesothelioma from two centers is reported. All cases were initially diagnosed between 1967 and 1986 utilizing laparoscopy and the histologic interpretation of laparoscopic biopsy samples. Subsequently, the original diagnosis was confirmed by two independent pathologists employing both histological and histochemical techniques. In five cases immunohistochemical studies were also performed. The clinical findings and course of the disease were similar to other reported series. Laparoscopic findings of mesothelioma were indistinguishable from metastatic peritoneal neoplasms. However, the presence of homogeneous spreading of nodules, plaques, or fleshy masses on both parietal and visceral peritoneum; the absence of direct or indirect signs of other abdominal neoplasms; and the absence of hepatic metastases or the possible presence of nodules or plaques on Glisson's capsule without any parenchymal involvement, when observed, allowed the laparoscopist to suspect the disease in four of 10 cases. Laparoscopy may be useful in detecting mesothelioma. The diagnosis is mainly morphological, but even morphology has its inherent limitations. Further studies are necessary to improve the diagnostic accuracy of this tumor.
E Piccigallo; L J Jeffers; K R Reddy; M W Caldironi; A Parenti; E R Schiff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestive diseases and sciences     Volume:  33     ISSN:  0163-2116     ISO Abbreviation:  Dig. Dis. Sci.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-06-02     Completed Date:  1988-06-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902782     Medline TA:  Dig Dis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  633-9     Citation Subset:  AIM; IM    
Diagnostic Laparoscopy Center, Padua Hospital, Italy.
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MeSH Terms
Mesothelioma / diagnosis*,  mortality,  pathology
Middle Aged
Peritoneal Neoplasms / diagnosis*,  mortality,  pathology
Peritoneum / pathology
Retrospective Studies

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