Document Detail

Malignant optic nerve glioma (glioblastoma multiforme): A case report and literature review.
MedLine Citation:
PMID:  17111679     Owner:  NLM     Status:  MEDLINE    
Primary gliomas of the optic nerve are very rare. We report a case of a 59-year-old male with sudden vision loss diagnosed with malignant optic nerve glioblastoma multiforme. Magnetic resonance imaging revealed thickening of optic tracts, chiasm, and hypothalamus. Histologically, the tumor was composed of glial cells with pleomorphic nuclei and areas of vascular proliferation and necrosis. The patient died eight weeks after initial presentation. In addition to our case, 30 previously reported cases of malignant optic nerve glioma are reviewed.
Paul H Hartel; Charles Rosen; Cris Larzo; Scott Nestor
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The West Virginia medical journal     Volume:  102     ISSN:  0043-3284     ISO Abbreviation:  W V Med J     Publication Date:    2006 Jul-Aug
Date Detail:
Created Date:  2006-11-20     Completed Date:  2006-12-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413777     Medline TA:  W V Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  29-31     Citation Subset:  IM    
Department of Pathology, West Virginia University School of Medicine, Morgantown, USA.
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MeSH Terms
Age Factors
Diagnosis, Differential
Glioblastoma / pathology
Magnetic Resonance Imaging
Middle Aged
Optic Nerve / pathology
Optic Nerve Glioma* / diagnosis,  epidemiology,  mortality,  pathology,  surgery
Sex Factors
Visual Fields

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