Document Detail

Malignant mesotheliomas in Kure City, Japan: the relationship of asbestos exposure.
MedLine Citation:
PMID:  2620245     Owner:  NLM     Status:  MEDLINE    
Eighteen patients with malignant mesothelioma were seen at Kure Mutual Aid Hospital over a 10-year period. According to occupational history, chest x-ray manifestations, and evidence of asbestos bodies in the tissue, 13 of these cases were definitely thought to be due to exposure to asbestos as a result of two or three of these items testing positive. Kure City is one of the major ship-building cities in Japan since the 1920s. Most of the 18 patients worked in ship building before and during World War II. Malignant mesothelioma appeared about 40 years after their first exposure to asbestos. In western countries, most malignant mesotheliomas are thought to be induced by exposure to asbestos fibers (1,2). Consequently, there has been a serious effort to deal with this problem recently, including lowering rate of exposure. In Japan, however, there have been few reports that asbestos fibers caused malignant mesothelioma (3). This report suggests that an increased incidence of malignant mesotheliomas in a specific area of Japan may also be due to exposure to asbestos fibers.
T Kishimoto; T Sato; T Ono; K Okada; Y Masuda; H Ito
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer investigation     Volume:  7     ISSN:  0735-7907     ISO Abbreviation:  Cancer Invest.     Publication Date:  1989  
Date Detail:
Created Date:  1990-03-20     Completed Date:  1990-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8307154     Medline TA:  Cancer Invest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  407-10     Citation Subset:  IM    
Department of Clinical Investigation, Kure Mutual Aid Hospital, Japan.
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MeSH Terms
Asbestos / adverse effects*
Environmental Exposure
Mesothelioma / etiology*
Middle Aged
Occupational Diseases / etiology*
Pleural Neoplasms / etiology*
Reg. No./Substance:

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