Document Detail

Malignant mental nerve neuropathy: systematic review.
MedLine Citation:
PMID:  18830167     Owner:  NLM     Status:  MEDLINE    
Malignant mental neuropathy (MMN) is a neurological manifestation of cancer, characterized by the presence of hypoesthesia or anesthesia restricted to the territory of the mental branch of the mandibular nerve. A systematic review of the literature has been made on MMN, analyzing the etiology, pathogeny, clinical characteristics, complementary tests and the prognosis. Sixteen studies, providing 136 cases were selected. Breast cancer and lymphomas were the most frequently associated malignant diseases. The most frequent pathogenic mechanisms producing neurological involvement were: peripherally, mandibular lesions; and centrally, tumors at the base of the cranium. Regarding clinical characteristics, manifestation of MMN was the primary symptom of malignant disease in 27.7% of cases, and a first symptom of recurrence in 37.7%. The group of selected studies included 50 orthopantomographs, 9 mandibular computed tomographies and 50 radiographic examinations of the cranial region. The most affected region was the mandible. The appearance of MMN is an ominous prognosis for the progression of the disease, with a mortality of 78.5% within a mean of 6.9 months.
Sónnica Galán Gil; Maria Peñarrocha Diago; Miguel Peñarrocha Diago
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-10-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  13     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-02     Completed Date:  2009-01-22     Revised Date:  2009-12-11    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  E616-21     Citation Subset:  D; IM    
Valencia University Medical and Dental School, Spain.
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MeSH Terms
Cranial Nerve Diseases / diagnosis,  etiology*
Mandibular Nerve*
Neoplasms / complications*

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