| Malignant melanoma and pregnancy: second thoughts. | |
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MedLine Citation:
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PMID: 19592319 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Malignant melanoma (MM) was considered a hormone-sensitive tumour, and pregnancy was thought to increase its risk and cause faster progression and earlier metastasis. Several controlled studies demonstrated similar survival rates between pregnant and non-pregnant patients and concluded that early reports of advanced MM of pregnancy were probably due to late diagnosis. We retrieved information from our database between 1997 and 2006 on all patients diagnosed as having MM during and up to 6 months after pregnancy (n=11) and compared them to age-matched, non-pregnant, MM patients (n=65, controls) treated by us during that period. The mean Breslow thickness was 4.28mm for the pregnant patients and 1.69mm for the controls (p=0.15). The sentinel nodes were metastatic in five pregnant patients compared to four controls (p<0.0001). Two patients in the pregnancy group and one control died of MM (p=0.0532). Our results indicate a negative effect of pregnancy on the course of MM. |
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Authors:
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Ehud Miller; Yoav Barnea; Eyal Gur; David Leshem; Eliad Karin; Jerry Weiss; Schlomo Schneebaum |
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Publication Detail:
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Type: Journal Article Date: 2009-07-09 |
Journal Detail:
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Title: Journal of plastic, reconstructive & aesthetic surgery : JPRAS Volume: 63 ISSN: 1878-0539 ISO Abbreviation: J Plast Reconstr Aesthet Surg Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-06-14 Completed Date: 2010-06-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101264239 Medline TA: J Plast Reconstr Aesthet Surg Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1163-8 Citation Subset: IM |
Copyright Information:
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Copyright 2009 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Tel-Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Disease Progression Female Humans Lymphatic Metastasis Melanoma / diagnosis, pathology*, secondary Pregnancy Pregnancy Complications, Neoplastic / diagnosis, pathology* Skin Neoplasms / diagnosis, pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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