Document Detail


Malignant melanoma in marathon runners.
MedLine Citation:
PMID:  17116838     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Marathon running has surged in popularity; it is generally believed to be healthy, but may be associated with medical risks. Over the past decade, we observed 8 ultramarathon runners with malignant melanoma. UV exposure, immunosuppression due to long-term intensive exercise, or both have been discussed as potential triggers in these patients. To further evaluate risk factors for malignant melanoma in marathon runners, we examined anamnestic, phenotypic, sun-related, and clinical variables in 210 athletes and compared them with those of an age- and sex-matched control group. OBSERVATIONS: Although control subjects exhibited higher sun sensitivity and more common melanocytic nevi, marathon runners presented with more atypical melanocytic nevi, solar lentigines, and lesions suggestive of nonmelanoma skin cancer. These findings correlated with increasing training intensity. During exercising, most runners wore shorts (96.7%) and shirts (98.6%) that would not or would only partially cover their back and extremities. Regular use of sunscreen was reported in only 56.2% of runners. CONCLUSIONS: Compared with a representative control group, marathon runners presented with an increased risk for malignant melanoma and nonmelanoma skin cancer. They should reduce UV exposure during exercising by choosing training and competition schedules with low sun exposure, wearing adequate clothing, and regularly using water-resistant sunscreens.
Authors:
Christina M Ambros-Rudolph; Rainer Hofmann-Wellenhof; Erika Richtig; Manuela Müller-Fürstner; H Peter Soyer; Helmut Kerl
Related Documents :
1152628 - Effect of warm-up on metabolic responses to strenuous exercise.
7552768 - Salbutamol and high-intensity treadmill running in nonasthmatic highly conditioned athl...
7786348 - Treadmill exercise training and estradiol differentially modulate hypothalamic-pituitar...
15976158 - Ventricular septal defect in a world class runner.
1474418 - The role of exercise in reducing coronary heart disease and associated risk factors.
15772058 - Early plateaus of power and torque gains during high- and low-speed resistance training...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  142     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-11-22     Completed Date:  2006-12-15     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1471-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Dermatology, Medical University of Graz, Graz, Austria. christina.ambros-rudolph@meduni-graz.at
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Austria / epidemiology
Case-Control Studies
Female
Humans
Male
Melanoma / epidemiology*,  etiology,  pathology,  prevention & control
Middle Aged
Phenotype
Pilot Projects
Protective Clothing
Running*
Skin Neoplasms / epidemiology*,  etiology,  pathology,  prevention & control
Sunlight / adverse effects
Sunscreening Agents
Chemical
Reg. No./Substance:
0/Sunscreening Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Livedoid vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity (4G/4G...
Next Document:  Hair depigmentation during chemotherapy with a class III/V receptor tyrosine kinase inhibitor.