| Malignant lesions of the liver identified on T1- but not T2-weighted MR images at 1.5 T. | |
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MedLine Citation:
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PMID: 8061427 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors reviewed their 2 1/2-year experience with a magnetic resonance (MR) imaging protocol for a 1.5-T MR imager that included T2-weighted fat-suppressed spin-echo, T1-weighted breath-hold gradient-echo, and serial dynamic gadolinium-enhanced T1-weighted gradient-echo imaging to identify histologic types of malignant liver lesions more apparent on T1- than on T2-weighted images. MR images of 212 consecutive patients with malignant liver lesions were reviewed. T2-weighted, T1-weighted, and dynamic contrast-enhanced T1-weighted images were examined separately in a blinded fashion. Seven patients demonstrated liver lesions (lymphoma [two patients] and carcinoid, hepatocellular carcinoma, colon adenocarcinoma, transitional cell carcinoma, and melanoma [one patient each]) on T1-weighted images that were inconspicuous on T2-weighted images. In all cases, the lesions were most conspicuous on T1-weighted images obtained immediately after administration of contrast agent. Histologic confirmation was present for all seven patients. The consistent feature among these lesions was that they were hypovascular, due either to a fibrous stroma or to dense monoclonal cellularity. These results suggest that in some patients with hypovascular primary neoplasms, the lesions may be identified only on T1-weighted images, and that immediate postcontrast T1-weighted images are of particular value in demonstrating lesions. |
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Authors:
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R C Semelka; A S Bagley; E D Brown; M A Kroeker |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 4 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 1994 May-Jun |
Date Detail:
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Created Date: 1994-09-20 Completed Date: 1994-09-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 315-8 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of North Carolina, Chapel Hill 27599-7510. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Contrast Media Drug Combinations Gadolinium / diagnostic use Gadolinium DTPA Humans Liver / pathology* Liver Neoplasms / diagnosis*, epidemiology, secondary Magnetic Resonance Imaging / methods* Male Meglumine / diagnostic use Middle Aged Organometallic Compounds / diagnostic use Pentetic Acid / analogs & derivatives, diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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