Document Detail

Malignant ganglioglioma: case report and review of literature.
MedLine Citation:
PMID:  20524041     Owner:  NLM     Status:  In-Process    
We report a case of de novo malignant ganglioglioma. A 61-year-old male presented with a 12-day history of headaches and general malaise. Pre-operative magnetic resonance imaging revealed an irregular enhancing mass in the left temporal lobe with associated dural enhancement and subacute subdural hematoma. The findings at surgery were of a vascular tumor intimately involving the surrounding white matter, with central necrosis. Histological and immunohistochemical studies showed an anaplastic ganglioglioma with World Health Organization grade IV characteristics. Gangliogliomas of the central nervous system are rare and are typified by a pediatric predilection and indolent behavior. A review of the de novo anaplastic and malignant gangliogliomas is presented.
Ryan DeMarchi; Suzy Abu-Abed; David Munoz; R Loch Macdonald
Publication Detail:
Type:  Journal Article     Date:  2010-06-04
Journal Detail:
Title:  Journal of neuro-oncology     Volume:  101     ISSN:  1573-7373     ISO Abbreviation:  J. Neurooncol.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309335     Medline TA:  J Neurooncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  311-8     Citation Subset:  IM    
Division of Neurosurgery, St Michael's Hospital, Keenan Research Centre, the Li Ka Shing Knowledge Institute, 30 Bond Street, Toronto, ON M5B 1W8, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cell...
Next Document:  Erlotinib therapy for central nervous system hemangioblastomatosis associated with von Hippel-Lindau...