Document Detail

Malignant fibrous histiocytoma: an ultrastructural study of eleven cases.
MedLine Citation:
PMID:  6311725     Owner:  NLM     Status:  MEDLINE    
Eleven cases of malignant fibrous histiocytoma were examined electron microscopically. In six of seven cases with storiform-fascicular histologic features and in two cases with a myxoid pattern, no malignant-appearing histiocyte-like cells were identified. The neoplastic cells were fibroblasts and myofibroblasts, occasionally admixed with lymphocytes and benign-appearing histiocytes. Only in the other three cases (two pleomorphic sarcomas and one tumor with a storiform-fascicular pattern) were malignant cells with the features of histiocytes identified. The authors propose that some neoplasms with a storiform-fascicular pattern would be more accurately classified as fibrosarcomas than as histiocytomas and speculate on the possible histogenesis of those tumors that do contain histiocyte-type cells.
M A Hoffman; G R Dickersin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human pathology     Volume:  14     ISSN:  0046-8177     ISO Abbreviation:  Hum. Pathol.     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  913-22     Citation Subset:  IM    
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MeSH Terms
Bone Neoplasms / pathology,  ultrastructure
Fibroblasts / ultrastructure
Histiocytes / ultrastructure
Histiocytoma, Benign Fibrous / etiology,  pathology,  ultrastructure*
Middle Aged
Retroperitoneal Neoplasms / pathology,  ultrastructure
Skin Neoplasms / pathology,  ultrastructure

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