Document Detail

Malignant fibrous histiocytoma. An electron microscopic study of 17 cases.
MedLine Citation:
PMID:  6269278     Owner:  NLM     Status:  MEDLINE    
The ultrastructural findings in 17 cases of malignant fibrous histiocytoma (MFH) are described. The tumors consisted of fibroblast-like cells and histiocyte-like cells in different proportions in different cases. Intermediate, undifferentiated, xanthomatous and multinucleated giant cells were also identified. In 12 of 17 cases myofibroblasts were evident. Acid phosphatase activity was detected cytochemically in the Golgi zone, endoplasmic reticulum and lysosomes (GERL) mainly within histiocyte-like cells, in three cases. These observations indicate that the GERL of the tumor cells are engaged in th formation of lysosomes. The polymorphic cellular composition, including undifferentiated cells, lends support to the concept that the MFH originates from a primitive multipotent undifferentiated mesenchymal cell.
M Tsuneyoshi; M Enjoji; N Shinohara
Related Documents :
6993638 - Ultrastructure of cells of the mononuclear-phagocyte series (mps) across the leprosy sp...
22481618 - The rho kinase inhibitor fasudil is involved in p53-mediated apoptosis in human hepatoc...
11502838 - Expression of adrenomedullin by human placental cytotrophoblasts and choriocarcinoma ja...
9808778 - Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at ...
12351748 - The influence of different retinal subcircuits on the nonlinearity of ganglion cell beh...
11369798 - Construction of stable coxsackievirus and adenovirus receptor-expressing 3t3-l1 cells.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Virchows Archiv. A, Pathological anatomy and histology     Volume:  392     ISSN:  0340-1227     ISO Abbreviation:  Virchows Arch A Pathol Anat Histol     Publication Date:  1981  
Date Detail:
Created Date:  1981-11-18     Completed Date:  1981-11-18     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  7505137     Medline TA:  Virchows Arch A Pathol Anat Histol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  135-45     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acid Phosphatase / analysis
Endoplasmic Reticulum / enzymology
Fibroblasts / ultrastructure
Golgi Apparatus / enzymology
Histiocytes / enzymology,  ultrastructure
Histiocytoma, Benign Fibrous / enzymology,  ultrastructure*
Lysosomes / enzymology
Microscopy, Electron
Middle Aged
Soft Tissue Neoplasms / enzymology,  ultrastructure*
Reg. No./Substance:
EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Reducing body myopathy--ultrastructure and classification (author's transl)
Next Document:  Effects of reserpine treatment on beta-adrenergic/adenylate cyclase modulate secretion and resynthes...