Document Detail

Malignant esophagogastric junction obstruction: efficacy of balloon dilation combined with chemotherapy and/or radiation therapy.
MedLine Citation:
PMID:  12616421     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the efficacy of balloon dilation combined with chemotherapy and/or radiation therapy for palliation of dysphagia due to malignant esophagogastric junction strictures. METHODS: Fluoroscopically guided balloon dilation was attempted in 20 patients. The causes of strictures were gastric adenocarcinoma (n = 10) and esophageal squamous cell carcinoma (n = 10). Scheduled chemotherapy and/or radiation therapy followed balloon dilation in all patients. RESULTS: There were no technical failures or major complications. After balloon dilation, 15 (75%) patients showed improvement of dysphagia. No patient complained of reflux esophagitis during the follow-up period. Among the 15 patients, seven needed no further treatment for palliation of dysphagia until their deaths. The remaining eight patients underwent repeat balloon dilation (n = 4) or stent placement (n = 4) 3-43 weeks (mean 15 weeks) after the initial balloon dilation because of recurrent dysphagia. CONCLUSION: Balloon dilation combined with chemotherapy and/or radiation therapy seems to be an easy and reasonably effective palliative treatment for malignant esophagogastric strictures.
Gi-Young Ko; Ho-Young Song; Heuk-Jin Hong; Kyu-Bo Sung; Tae-Seok Seo; Hyun-Ki Yoon
Publication Detail:
Type:  Journal Article     Date:  2003-03-06
Journal Detail:
Title:  Cardiovascular and interventional radiology     Volume:  26     ISSN:  0174-1551     ISO Abbreviation:  Cardiovasc Intervent Radiol     Publication Date:    2003 Mar-Apr
Date Detail:
Created Date:  2003-06-18     Completed Date:  2003-12-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8003538     Medline TA:  Cardiovasc Intervent Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-5     Citation Subset:  IM    
Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1, Poongnap-Dong, Songpa-Ku, Seoul 138-736, Korea.
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MeSH Terms
Aged, 80 and over
Balloon Dilatation
Blood Vessel Prosthesis
Chemotherapy, Adjuvant
Combined Modality Therapy
Deglutition Disorders / etiology,  mortality
Esophageal Diseases / mortality,  therapy*
Esophagogastric Junction / surgery*
Follow-Up Studies
Gastric Outlet Obstruction / mortality,  therapy*
Middle Aged
Postoperative Complications / etiology,  mortality,  surgery
Radiotherapy, Adjuvant
Severity of Illness Index
Survival Analysis
Treatment Outcome

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