Document Detail

Malignant diseases and mortality in blood donors infected with human T-lymphotropic virus type 1 in Israel.
MedLine Citation:
PMID:  23642569     Owner:  NLM     Status:  Publisher    
OBJECTIVES: The natural history of blood donors infected with human T-lymphotropic virus type 1 (HTLV-1) in Israel has never been assessed. The aim of this study was to evaluate the prevalence of malignant disorders and mortality among a cohort of Israelis diagnosed as HTLV-1 carriers during routine blood unit screening. METHODS: This was an observational retrospective cohort study. All HTLV-1 cases among Israeli blood donors between 1995 and 2009 were included. Data regarding malignant diseases were extracted from the Israel National Cancer Registry. Mortality data were extracted from the Israel Population Registry. RESULTS: Between January 9, 1995 and December 31, 2009, 1574497 blood donors were screened for HTLV-1 in the central blood bank services. Of these, 90 were found to be HTLV-1 carriers. This cohort of HTLV-1-infected blood donors was followed for an average of 9.2±6 years. Among them six (6.7%) were diagnosed as having malignant diseases, four of them with adult T-cell leukemia/lymphoma (ATLL). The incidence of ATLL was 0.37 (95% confidence interval 0.13-1.08)/100 HTLV-1 carrier-years. CONCLUSIONS: We found a high rate of malignant diseases among HTLV-1-infected blood donors.
Shmuel Stienlauf; Vered Yahalom; Eilat Shinar; Yechezkel Sidi; Gad Segal; Eli Schwartz
Related Documents :
7468269 - Transcapillary exchange and distribution of carbon-11 labelled ethanol in the isolated ...
15741019 - An evaluation of internal carotid artery and cerebral blood flow volume using color dup...
2081149 - Non-invasive and simultaneous cardiovascular measurements using plethysmography techniq...
8215949 - Continuous on-line optical absorbance recording of blood volume changes during hemodial...
23642569 - Malignant diseases and mortality in blood donors infected with human t-lymphotropic vir...
3555089 - Placental volume measurement by ultrasonography: evaluation of the method.
14172639 - Blood groups of chimpanzees: demonstrated with isoimmune serums.
23106209 - Effects of gsm 900 mhz on middle cerebral artery blood flow assessed by transcranial do...
9493579 - Initiation and propagation of blood coagulation at artificial surfaces studied in a cap...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-4-30
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  -     ISSN:  1878-3511     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-5-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
Department of Medicine C, Sheba Medical Center, Tel Hashomer, 52621 Israel; The Center of Geographic Medicine, Sheba Medical Center, Tel Hashomer, Israel; Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel. Electronic address:
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Prevalence of intestinal protozoa in communities along the Lake Victoria region of Uganda.
Next Document:  Straw management effects on CO2 efflux and C storage in different Mediterranean agricultural soils.