Document Detail

Malignant aneuploid spindle-cell transformation in a proliferating trichilemmal tumour.
MedLine Citation:
PMID:  7906459     Owner:  NLM     Status:  MEDLINE    
A case of spindle-cell carcinoma developed on a proliferating trichilemmal tumour (PTT) is presented. The tumour on the scalp of an 84-year-old white woman was excised and histological examination showed typical features of PTT, but with a coexistent malignant spindle-cell tumour with a sarcomatoid appearance. There were some areas of transition between squamous trichilemmal epithelium and the neoplastic mass composed of atypical spindle-shaped cells. Two years later, the patient was well, and neither recurrence nor metastases were observed. We report the second case of PTT with a malignant spindle-cell transformation with a sarcomatoid appearance (spindle-cell carcinoma), and a proven aneuploidy, demonstrated with DNA-flow cytometric analysis.
M Alvarez-Quiñones; M F Garijo; F Fernández; J F Val-Bernal
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  73     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-03-18     Completed Date:  1994-03-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  444-6     Citation Subset:  IM    
Department of Pathology, University Hospital Marqués de Valdecilla, Santander, Spain.
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MeSH Terms
Aged, 80 and over
Carcinoma / pathology*
Cell Transformation, Neoplastic
Epidermal Cyst / pathology*
Scalp Dermatoses / pathology*
Skin Neoplasms / pathology*

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