Document Detail

Malignant adnexal neoplasms.
MedLine Citation:
PMID:  16446719     Owner:  NLM     Status:  MEDLINE    
Malignant cutaneous adnexal neoplasms are one of the most challenging areas of dermatopathology. Tumors of the pilosebaceous apparatus can occur as single-lineage neoplasms or may manifest as complex proliferations with multilineal differentiation patterns including not only the germinative component of the hair bulb, the inner or outer root sheath epithelium and the sebaceous gland and duct, but also the sweat duct components that relate to the apocrine secretory apparatus which empties into the follicle near the follicular bulge. Eccrine and apocrine neoplasms present a bewildering array of morphologies, which often defy precise classification. The purpose of this review is to discuss in detail the malignant neoplasms of the cutaneous adnexae and their benign and prognostically indeterminate mimics.
A Neil Crowson; Cynthia M Magro; Martin C Mihm
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc     Volume:  19 Suppl 2     ISSN:  0893-3952     ISO Abbreviation:  Mod. Pathol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-31     Completed Date:  2006-03-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8806605     Medline TA:  Mod Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S93-S126     Citation Subset:  IM    
Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114-4109, USA.
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MeSH Terms
Diagnosis, Differential
Mucin-1 / analysis
Sebaceous Glands / chemistry,  pathology*
Skin Neoplasms / metabolism,  pathology*
Reg. No./Substance:

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