Document Detail

Malignant transformation of a chronic venous stasis ulcer to basal cell carcinoma in a diabetic patient: case study and review of the pathophysiology.
MedLine Citation:
PMID:  20123293     Owner:  NLM     Status:  MEDLINE    
The degeneration of chronic wounds into basal cell carcinoma is rare. We present an atypical case of basal cell carcinoma diagnosed by soft tissue biopsy in a long-standing wound that had been treated for 3 years as a chronic venous stasis ulcer. In addition to the case report, we review the biomedical literature describing malignant transformation of long-standing wounds. Foot and ankle specialists should be on the lookout for changes that signal malignant transformation in long-standing ulcers.
Molly Schnirring-Judge; Drew Belpedio
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons     Volume:  49     ISSN:  1542-2224     ISO Abbreviation:  J Foot Ankle Surg     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9308427     Medline TA:  J Foot Ankle Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  75-9     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
Faculty Graduate Medical Education, Mercy Hospital Health Systems, Toledo, OH, USA.
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MeSH Terms
Aged, 80 and over
Carcinoma, Basal Cell / pathology*
Cell Transformation, Neoplastic*
Diabetes Mellitus, Type 1*
Skin Neoplasms / pathology*
Varicose Ulcer / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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