Document Detail

Malignant schwannoma in pregnancy: a case report and literature review.
MedLine Citation:
PMID:  19688672     Owner:  NLM     Status:  MEDLINE    
Malignant peripheral nerve sheath tumors in pregnancy are an uncommon finding. This diagnosis in a pregnant patient with neurofibromatosis type 1 poses additional treatment dilemmas. A 28-year-old primigravida with known neurofibromatosis type 1 complained of increasing shortness of breath and cough. Evaluation revealed a large chest mass, biopsy proven to be a malignant schwannoma. This malignant peripheral nerve sheath tumor, discovered at 26 weeks' gestation, grew so rapidly that delivery was necessary at 30 weeks' gestation. Management of pregnant patients with rare, rapidly growing tumors may require early delivery in cases where maternal health is in jeopardy.
Ann Kellogg; William J Watson
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-08-17
Journal Detail:
Title:  American journal of perinatology     Volume:  27     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-05-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  201-4     Citation Subset:  IM    
Copyright Information:
Thieme Medical Publishers.
Obstetrics and Gynecology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.
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MeSH Terms
Bone Neoplasms / secondary
Cesarean Section
Fatal Outcome
Lung Neoplasms / pathology*,  radiography,  surgery
Lymphatic Metastasis
Neoplasms, Second Primary / pathology*,  radiography,  surgery
Neurilemmoma / pathology*,  radiography,  secondary,  surgery
Neurofibromatosis 1 / diagnosis*
Pregnancy Complications, Neoplastic / pathology*,  radiography,  surgery
Pregnancy Outcome
Prenatal Care / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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