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Malignant Renal Angiomyolipoma With Metastases in a Child.
MedLine Citation:
PMID:  23975831     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The biological character of epithelioid angiomyolipoma (EAML) remains controversial and little is known about EAML in children. We present a case of a 7-year-old boy with abdominal distention, diagnosed as EAML. Under microscopy, epithelioid cells were observed, with eosinophilic or slightly eosinophilic cytoplasm and nuclear pleomorphism, thick-walled blood vessels, and some cells that were differentiated to smooth muscle cells or fat cells were easily observed. Immunochemical staining showed that Melan-A and HMB45 were positive. The tumor presented highly aggressive biobehavior. Furthermore, we reviewed and analyzed cases of diagnosed EAML in our hospital and those reported in the literature. Renal EAML (10/17) was most common, and the EAML of 3 of 17 patients metastasized to other organs.
Authors:
Shaoyan Xi; Huadong Chen; Xingping Wu; Hong Jiang; Juncheng Liu; Qiuliang Wu; Jing Zeng
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-8-22
Journal Detail:
Title:  International journal of surgical pathology     Volume:  -     ISSN:  1940-2465     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2013-8-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Sun Yat-sen University Cancer Center, Guangzhou, China.
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