| Malformations of the posterior fossa: current perspectives. | |
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MedLine Citation:
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PMID: 12523556 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Posterior fossa malformations are a special group of central nervous system anomalies that present during infancy with hypotonia, developmental delay, microcephaly, or hydrocephalus. Recent discoveries of the genetic and epigenetic factors that control hindbrain ontogenesis explain some of these disturbances in cerebellar development. A comprehensive classification of posterior fossa malformations is proposed with particular attention to Dandy-Walker malformation, Joubert syndrome, and other cerebellar hypoplasias. A rare form of cerebellar hypertrophy which caused repeated obstruction at the foramen magnum is recognized. The importance of the cerebellum in language, cognition, and brain growth is stressed. |
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Authors:
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Charles E Niesen |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in pediatric neurology Volume: 9 ISSN: 1071-9091 ISO Abbreviation: Semin Pediatr Neurol Publication Date: 2002 Dec |
Date Detail:
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Created Date: 2003-01-13 Completed Date: 2003-03-05 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9441351 Medline TA: Semin Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 320-34 Citation Subset: IM |
Affiliation:
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Division of Pediatric Neurology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arnold-Chiari Malformation
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diagnosis Cerebellum / abnormalities, embryology Cognition Cranial Fossa, Posterior / abnormalities*, embryology Dandy-Walker Syndrome / diagnosis, genetics Diagnosis, Differential Humans Language Development Magnetic Resonance Imaging Nervous System Malformations / diagnosis, genetics* Pons / abnormalities Rhombencephalon / abnormalities*, embryology Syndrome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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