Document Detail

Male obesity and alteration in sperm parameters.
MedLine Citation:
PMID:  18178190     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the effect of male obesity on sperm parameters and erectile dysfunction. DESIGN: Retrospective analysis. SETTING: Referral fertility center. PATIENT(S): Couples presenting for infertility treatment. INTERVENTION(S): On presentation, all men reported their weight and height and filled out an intake form that includes questions regarding factors that affect male infertility, including presence of erectile dysfunction. Body mass index (BMI) was divided into three groups: normal (BMI <25 kg/m(2)), overweight (25 kg/m(2) <or= BMI < 30 kg/m(2)), and obese (BMI >or=30 kg/m(2)). Sperm parameters reviewed included sperm concentration and progressively motile sperm count. MAIN OUTCOME MEASURE(S): Oligozoospermia, low progressively motile sperm count, and self-reported erectile dysfunction. RESULT(S): The mean age of the study population was 32.8 +/- 0.3 years. Among the 526 patients, 10.2% (54 of 526) were excluded because of the presence of a male factor known to affect fertility. The incidence of oligozoospermia increased with increasing BMI: normal weight = 5.32%, overweight = 9.52%, and obese = 15.62%. The prevalence of a low progressively motile sperm count was also greater with increasing BMI: normal weight = 4.52%, overweight = 8.93%, and obese = 13.28%. The incidence of erectile dysfunction did not vary across BMI categories when corrected for potential contributing factors. CONCLUSION(S): Male obesity is associated with increased incidence of low sperm concentration and low progressively motile sperm count.
Ahmad O Hammoud; Nicole Wilde; Mark Gibson; Anna Parks; Douglas T Carrell; A Wayne Meikle
Publication Detail:
Type:  Journal Article     Date:  2008-02-21
Journal Detail:
Title:  Fertility and sterility     Volume:  90     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-01     Completed Date:  2008-12-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2222-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, University of Utah, School of Medicine, Salt Lake City, Utah 84132, USA.
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MeSH Terms
Body Mass Index
Erectile Dysfunction / epidemiology,  etiology*,  pathology
Obesity / complications*,  epidemiology,  pathology
Odds Ratio
Oligospermia / epidemiology,  etiology*,  pathology
Retrospective Studies
Risk Assessment
Sperm Count
Sperm Motility
Spermatozoa / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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