| Male lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH). | |
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MedLine Citation:
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PMID: 21095413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Male lower urinary tract symptoms, benign prostatic hyperplasia, enlargement of the prostate, and bladder outlet obstruction are common among aging men and will increase in socioeconomic and medical importance at a time of increased life expectancy and aging of the baby boomer generation. This article reviews the epidemiology, management, and therapeutic options for these conditions. In patients bothered by moderate to severe symptoms, providers can make educated and differential choices between several classes of drugs, alone or in combination, to treat effectively and improve the symptoms in most men. Despite the efficacy of medical therapy, there will be patients who require referral to a urologist either early, to rule out prostate cancer and other conditions, or later, after initial medical therapy and lifestyle management has failed. Perhaps as many as 30% of patients fail to achieve sufficient symptom improvement with medication, lifestyle adjustment, and fluid management, and may require more invasive or surgical treatment options. |
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Authors:
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Claus G Roehrborn |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Medical clinics of North America Volume: 95 ISSN: 1557-9859 ISO Abbreviation: Med. Clin. North Am. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-11-24 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985236R Medline TA: Med Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 87-100 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Urology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, J8 142, Dallas, TX 75390-9110, USA. claus.roehrborn@utsouthwestern.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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5-alpha Reductase Inhibitors
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therapeutic use Adrenergic alpha-Antagonists / therapeutic use Humans Male Muscarinic Antagonists / therapeutic use Plant Extracts / therapeutic use Primary Health Care* Prostate-Specific Antigen Prostatic Hyperplasia / complications, drug therapy*, therapy Urinary Incontinence / drug therapy*, etiology, therapy |
| Chemical | |
Reg. No./Substance:
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0/5-alpha Reductase Inhibitors; 0/Adrenergic alpha-Antagonists; 0/Muscarinic Antagonists; 0/Permixon; 0/Plant Extracts; EC 3.4.21.77/Prostate-Specific Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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