Document Detail

Malassezia furfur meningitis associated with total parenteral nutrition subdural effusion.
MedLine Citation:
PMID:  15255040     Owner:  NLM     Status:  MEDLINE    
We present a case of Malassezia furfur meningitis arising in a very low birth weight infant with chronic lung disease, necrotizing enterocolitis, and intraventricular hemorrhage. M. furfur meningitis was probably acquired late following successful treatment for earlier systemic central line-associated M. furfur infection. M. furfur meningitis has only once been previously reported. Unlike the previous case where meningitis was secondary to widespread blood-borne dissemination, infection was limited to the leptomeninges and arose in association with extravasation of total parenteral nutrition (TPN) and intralipid fluid into subarachnoid space via peripheral scalp catheter.
Cecilia M Rosales; Mary Anne Jackson; David Zwick
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  7     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2004 Jan-Feb
Date Detail:
Created Date:  2004-07-16     Completed Date:  2004-11-02     Revised Date:  2006-05-08    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-90     Citation Subset:  IM    
Department of Pathology, Truman Medical Center, 2301 Holmes Street, Kansas City, MO 64108, USA.
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MeSH Terms
Amphotericin B / therapeutic use
Antifungal Agents / therapeutic use
Catheterization / adverse effects
Catheterization, Central Venous / adverse effects
Cerebral Hemorrhage / complications
Chronic Disease
Enterocolitis, Necrotizing / complications
Fat Emulsions, Intravenous / adverse effects
Fatal Outcome
Infant, Low Birth Weight
Infant, Newborn
Lung Diseases / complications
Meningitis, Fungal / complications,  drug therapy,  etiology*
Parenteral Nutrition, Total / adverse effects*,  instrumentation
Subdural Effusion / etiology*,  pathology
Reg. No./Substance:
0/Antifungal Agents; 0/Fat Emulsions, Intravenous; 1397-89-3/Amphotericin B

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