Document Detail


Malaria in pregnant woman masquerading as HELLP syndrome.
MedLine Citation:
PMID:  19626579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Malaria may be complicated by development of thrombocytopenia, elevated liver enzymes, and/or hemolysis, which may be difficult to distinguish from HELLP (hemolytic anemia; elevated liver enzymes; low platelet count) syndrome in a pregnant patient. A 33-year-old woman developed a HELLP-like syndrome and persistent fever postpartum without symptoms of preeclampsia. A malaria blood smear was performed and was positive for Plasmodium falciparum. The patient was immediately treated with quinine. The follow-up was uneventful with total disappearance of fever and prompt resolution of biochemical signs of HELLP-like syndrome 3 days later. Malaria in a pregnant woman can masquerade as HELLP syndrome. The wide overlap in symptoms (headache, malaise, digestive symptoms) does not suggest that symptoms would be effective in differentiating malaria and preeclampsia. A recent travel in endemic area, associated with malaria blood smear and clinic examination, should be the key of the differential diagnosis.
Authors:
Guillaume Ducarme; Claire Thuillier; Anne Wernet; Claire Bellier; Dominique Luton
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-07-22
Journal Detail:
Title:  American journal of perinatology     Volume:  27     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-22     Completed Date:  2010-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  171-2     Citation Subset:  IM    
Copyright Information:
Thieme Medical Publishers.
Affiliation:
Department of Obstetrics and Gynecology, H?pital Beaujon, Assistance Publique-H?pitaux de Paris, 100, Boulevard du G?n?ral Leclerc, 92110 Clichy, France. g.ducarme@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Antimalarials / therapeutic use
Diagnosis, Differential
Female
Fever / parasitology
HELLP Syndrome / diagnosis
Humans
Malaria, Falciparum / diagnosis*,  drug therapy
Plasmodium falciparum / isolation & purification
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Quinine / therapeutic use
Chemical
Reg. No./Substance:
0/Antimalarials; 130-95-0/Quinine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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