| Transfusion-transmitted malaria in countries where malaria is endemic: a review of the literature from sub-Saharan Africa. | |
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MedLine Citation:
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PMID: 20929356 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Although international policies recommend that blood for transfusion should be screened for transfusion-transmitted infections, malaria screening is not performed in most malaria-endemic countries in sub-Saharan Africa. Our literature review identified 17 relevant studies from the period 1980-2009 and indicated that the median prevalence of malaria among 33,029 blood donors was 10.2% (range, 0.7% in Kenya to 55.0% in Nigeria). Malaria screening methods, including microscopy (used in 16 of 17 studies), are either insensitive or impractical for donor screening in resource-poor countries. Even if a suitable screening method were available, rejection of malaria-positive donors would jeopardize the blood supply. Only 1 study established the prevalence of parasitemia among transfusion recipients. This review highlights the need for more evidence about the clinical impact of transfusion-transmitted malaria to justify the policy of screening for blood for malaria in areas of endemicity and for a critical analysis of the feasibility of implementing such a policy and its effect on blood supply. |
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Authors:
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Alex K Owusu-Ofori; Christopher Parry; Imelda Bates |
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Publication Detail:
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Type: Journal Article Date: 2010-10-07 |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 51 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 1192-8 Citation Subset: IM |
Affiliation:
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Department of Clinical Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana. Alex.owusu-ofori@liv.ac.uk |
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| Comments/Corrections | |
Comment In:
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Clin Infect Dis. 2010 Nov 15;51(10):1199-200
[PMID:
20929357
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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