Document Detail


Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea.
MedLine Citation:
PMID:  3057189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Proguanil 200mg daily and chloroquine base 300mg weekly along with maloprim 1 tablet weekly was used as malaria chemoprophylaxis for 140 Hong Kong based soliders on a seven-week jungle exercise in a holoendemic malarial area of Papua New Guinea. On return from exercise all personnel were treated with primaquine 7.5mg three times daily for a two week period. One solider developed P. falciparum on the exercise whilst taking chemoprophylaxis and four subsequently developed P. vivax malaria after cessation of chemoprophylaxis.
Authors:
B J Heap
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Royal Army Medical Corps     Volume:  134     ISSN:  0035-8665     ISO Abbreviation:  J R Army Med Corps     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1989-01-11     Completed Date:  1989-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7505627     Medline TA:  J R Army Med Corps     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  128-9     Citation Subset:  IM    
Affiliation:
British Military Hospital, Hong Kong.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antimalarials / administration & dosage*,  urine
Chloroguanide / administration & dosage,  urine
Chloroquine / administration & dosage
Dapsone / administration & dosage
Drug Combinations / administration & dosage
Drug Therapy, Combination
Humans
Malaria / prevention & control*,  urine
Military Personnel
Papua New Guinea
Plasmodium falciparum
Plasmodium vivax
Pyrimethamine / administration & dosage
Chemical
Reg. No./Substance:
0/Antimalarials; 0/Drug Combinations; 37357-69-0/Maloprim; 500-92-5/Chloroguanide; 54-05-7/Chloroquine; 58-14-0/Pyrimethamine; 80-08-0/Dapsone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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