| Malakoplakia presenting as an enlarging neck mass: Case presentation and review of the literature. | |
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MedLine Citation:
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PMID: 19626641 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Malakoplakia is a very rare chronic inflammatory disorder, first described in 1902. In 75% of cases, the condition affects the genitourinary tract. Five cases of malakoplakia affecting the neck were previously reported in the literature. METHODS AND RESULTS: An 83-year-old woman presented with an enlarging mass in the posterior triangle of the neck that was histologically confirmed as malakoplakia. Presenting features are often nonspecific, and the diagnosis is dependent on histological findings. The characteristic microscopic findings are of Michaelis-Gutmann (M-G) bodies that stain positive with periodic acid-Schiff reagent, von Kossa's reaction for calcium, and Perl's ferrocyanide reaction to ferric iron. CONCLUSION: Although rare, a diagnosis of malakoplakia should be considered in patients with an enlarging mass. This may mimic the presentation of malignancy, particularly in patients in whom erosion through skin occurs, and histological confirmation is advocated. |
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Authors:
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Montey Garg; Karen A Eley; Stephen E Bond; Ketan A Shah; Lisa Browning; Stephen R Watt-Smith |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Head & neck Volume: 32 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-12-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 1269-72 Citation Subset: IM |
Affiliation:
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Department of Maxillofacial Surgery, Oxford Radcliffe Hospitals NHS Trust, Oxford, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Biopsy, Needle Diagnosis, Differential Female Follow-Up Studies Head and Neck Neoplasms / diagnosis, pathology* Humans Immunohistochemistry Malacoplakia / diagnosis, pathology*, surgery* Neck / pathology*, surgery Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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